It is conveniently located overlooking the entire city of San Francisco. Its business school is well known in California, especially in entrepreneurship and entrepreneurial management, and is known as the cradle of entrepreneurial executives, surpassing Stanford University and UCLA. In addition, the combination of proximity to Silicon Valley makes computer science particularly sought-after, allowing students to interact and engage with leading entrepreneurs and to participate and work on new projects.

SLU is the oldest private university in the Mississippi River Basin. It has 90 undergraduate majors and more than 100 graduate majors, 15 of which are ranked in the top 50 in the nation, and biology, sports rehabilitation, nursing and kinesiology and physical therapy are ranked in the top 10.

The school is ranked among the top 15 in the nation for finance and accounting, as well as for nursing, chemistry, and psychology. Creighton's School of Business is accredited by AACSB International and has the highest number of faculty members holding the CFA designation in the world.

The university was founded in 1877, it has more than 130 academic programs at different levels, with majors such as applied sciences and communications focusing on the perfect combination of application and theory, as well as the integrated development of academics and employment.

It has been listed in one of the 40 "Colleges that Change Lives". It is a private liberal arts college with a very long history in Pennsylvania.